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| Catalog Code: | NB110-60935 |
| Product Name: | FTO Antibody |
| Product Description: | Rabbit Polyclonal anti-FTO |
| Clonality: | Polyclonal |
| ListPrice: | 285 |
| Gene ID: | 79068 |
| Concentration: | 1.1 mg/ml |
| Immunogen: | A synthetic peptide within the C-terminal region (residues 400-505) of the human protein. [Swiss-Prot# Q9C0B1] |
| Cross Reactivity: | Human. Other species not yet tested. |
| Packaging: | 0.1 ml peptide affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for Western blot analysis, where a band is seen at ~60 kDa. |
| Background: | FTO is a novel protein and a member of the non-heme dioxygenase (Fe(II)- and 2-oxoglutarate-dependent dioxygenases) superfamily. Amino acid conservation patterns support this hypothesis and indicate that both 2-oxoglutarate and iron should be important for FTO function. Though not much is yet known about FTO, it is thought that the protein may somehow modify the activity of genes involved in metabolism and fat storage, which in turn may influence a person's risk of obesity. |
| Storage: | Store at 4C for short-term. Aliquot and store at -20C for long term. Avoid freeze-thaw cycles. |
| Purity: | peptide affinity purified |
| Host Name: | Rabbit |
| Buffer: | Tris-citrate/phosphate [pH 7-8] |
| Application Summary: | Western Blot 0.5 ug/ml |
| Species Summary: | Hu, |
| Alternate Names: | anti-fat mass and obesity associated protein antibody, anti-fatso antibody, anti-MGC5149 antibody, anti-KIAA1752 antibody |
| Package Size: | 0.1 ml |
| Preservative: | 0.1% sodium azide |
| Homology: | 100% homology with human, monkey, and mouse proteins. |
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more information: | company product webpage |