| CatalogCode: | NB110-60530 |
| ProductName: | S100A Antibody |
| Product Description: | Mouse Monoclonal anti-S100A (2C8B8, 2C8E8) |
| Clone: | 2C8B8, 2C8E8 |
| Clonality: | Monoclonal |
| Immunogen: | Ni-NTA purified truncated recombinant S100A expressed in E. Coli strain BL21 (DE3) |
| CrossReactivity: | Human |
| Packaging: | 0.1 ml protein A purified Mouse ascites. |
| Uses: | This antibody is useful for Western blot and ELISA. |
| Background: | S100 calcium binding protein A1 (S100-alpha/ S100A1), The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. |
| Storage: | Store at 4C for short term. Aliquot and store at -20C for long term. Avoid freeze-thaw cycles. |
| Purity: | protein A purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| PackageSize: | 0.1 ml |
| GeneralRef: | 1. Koenig A, Wojcieszyn J, Weeks BR, et al. Vet Pathol. 2001;38(4):427-35. 2. Hoyaux D, Decaestecker C, Heizmann CW, et al. Brain Res. 2000;867(1-2):280-8. 3. Pingerelli PL, Mizukami H, Wagner AS, et al. J Protein Chem. 1990;9(2):169-75. |
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