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| Catalog Code: | NB110-60507 |
| Product Name: | Myoglobin Antibody |
| Product Description: | Mouse Monoclonal anti-Myoglobin (6H8B5) |
| Clone: | 6H8B5 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Ni-NTA purified truncated recombinant Myoglobin expressed in E. Coli strain BL21 (DE3) |
| Cross Reactivity: | Human |
| Packaging: | 0.1 ml Mouse ascites. |
| Uses: | This antibody is useful in Western Blot, IHC(P), IHC(F), and ELISA1: 10,000 |
| Background: | Myoglobin (MB), with 154-amino acid protein (about 17kDa), is a member of the globin superfamily and expression of myoglobin is highest in skeletal and cardiac muscle. Functionally, myoglobin is well accepted as an O2-storage protein in muscle, capable of releasing O2 during periods of hypoxia or anoxia. Myoglobin is also thought to buffer intracellular O2 concentration when muscle activity increases and to facilitate intracellular O2 diffusion by providing a parallel path that augments simple diffusion of dissolved O2. Furthermore, myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis. |
| Storage: | Store at 4C for short term. Aliquot and store at -20C for long term. Avoid freeze-thaw cycles. |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Application Summary: | ELISA 1:10000, Western Blot 1:500-1:2000, Immunohistochemistry-Paraffin 1:500-1:2000, Immunohistochemistry-Frozen 1:500-1:2000 |
| Species Summary: | Hu, |
| Package Size: | 0.1 ml |
| General References: | 1. George A. Ordway, Daniel J. Garry J. Exp. Biol., Sep 2004; 207: 3441-3446 2. Ulrich Floel, Tim Laussmann, Axel Goecke Circ. Res., Apr 2005; 96: e68 - e75 |
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