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| Catalog Code: | NB110-60501 |
| Product Name: | CK1 Antibody |
| Product Description: | Mouse Monoclonal anti-CK1 (3C10F7) |
| Clone: | 3C10F7 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Ni-NTA purified truncated recombinant CK1 expressed in E. Coli strain BL21 (DE3) |
| Cross Reactivity: | Human |
| Packaging: | 0.1 ml Ascites Mouse ascites. |
| Uses: | This antibody is useful in Western Blot, IHC(P), IHC(F), and ELISA. |
| Background: | CK1 (also designated Cytokeratin 1 or KRT1 ),with 644-amino acid protein (about 70kDa), is a member of the keratin family. Cytokeratins play a critical role in differentiation and tissue specialization, and they function to maintain the overall structural integrity of epithelial cells.CK1 consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. CK1 is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. |
| Purity: | Ascites |
| Host Name: | Mouse |
| Application Summary: | ELISA 1:10000, Western Blot 1:500- 1:2000, Immunohistochemistry-Paraffin 1:500- 1:2000, Immunohistochemistry-Frozen 1:500- 1:2000 |
| Species Summary: | Hu, |
| Package Size: | 0.1 ml |
| General References: | 1. Ricardo G. Espinola, Robin A. Pixley, Berhane Ghebrehiwet Blood (ASH Annual Meeting Abstracts), Nov 2005; 106: 2666 |
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