| CatalogCode: | NB110-60497 |
| ProductName: | SNCG Antibody |
| Product Description: | Mouse Monoclonal anti-SNCG (1H10D2) |
| Clone: | 1H10D2 |
| Clonality: | Monoclonal |
| Immunogen: | Ni-NTA purified truncated recombinant SNCG expressed in E. Coli strain BL21 (DE3) |
| CrossReactivity: | Human |
| Packaging: | 0.1 ml protein A purified Mouse ascites. |
| Uses: | This antibody is useful in Western Blot, IHC(P), IHC(F), and ELISA. |
| Background: | SNCG(also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development. |
| Storage: | Store at -20 degrees |
| Purity: | protein A purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB, IHC-P, IHC-Fr |
| SpeciesSummary: | Hu |
| ALTnames: | anti-breast cancer-specific protein 1 antibody |
| PackageSize: | 0.1 ml |
| GeneralRef: | 1. Haiyan Liu, Wei Liu, Yinwei Wu Cancer Res. 2005 Sep 1;65(17):7635-43 2. Irina Surgucheva , Belinda McMahon , Andrei Surguchov Cell Motil Cytoskeleton. 2006 May 26 |
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