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| Catalog Code: | NB110-60486 |
| Product Name: | LSD1/AOF2 Antibody |
| Product Description: | Mouse Monoclonal anti-LSD1/AOF2 (1B2F2) |
| Clone: | 1B2F2 |
| Clonality: | Monoclonal |
| ListPrice: | 435 |
| Immunogen: | Ni-NTA purified truncated recombinant human LSD1 expressed in E. Coli strain BL21 (DE3) |
| Cross Reactivity: | Human |
| Packaging: | 0.1 ml protein A purified Mouse ascites. |
| Uses: | This antibody is useful for Western Blot, IHC(P), IHC(F) and ELISA |
| Background: | The amine oxidase domain 2£šAOF2£©gene encodes a nuclear protein(LSD1,~95kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex(es) on chromatin. |
| Storage: | Store at -20 degrees |
| Purity: | protein A purified |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Application Summary: | ELISA 1: 10000, Western Blot 1: 500- 1: 2000, Immunohistochemistry-Paraffin 1: 500- 1: 2000, Immunohistochemistry-Frozen 1: 500- 1: 2000 |
| Species Summary: | Hu, |
| Package Size: | 0.1 ml |
| General References: | 1 Shi YJ, et.al Mol Cell. 2005 Sep 16;19(6):857-64. 2 Metzger E, et.al Nature. 2005 Sep 15;437(7057):436-9. |
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