| Catalog Code: | NB110-60483 |
| Product Type: | Primary Antibody |
| Product Name: | RAD50 Antibody |
| List Price: | 325 |
| Clonality: | Polyclonal |
| Gene ID: | 10111 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-RAD50 |
| Cross Reactivity: | Human. Reactivity with mouse and rat likely due to 100% sequence homology. |
| Species Summary: | Hu |
| Background: | The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic |
| Alternate Names: | anti-hRAD50 antibody, anti-RAD50-2 antibody |
| Immunogen: | Between residues 50 and 100 of human Rad50 [NP_005723.2] |
| Purity: | Immunogen affinity purified |
| Buffer: | Tris-citrate/phosphate buffer, pH 7-8 |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Package Size: | 0.1 ml |
| Concentration: | 1 mg/ml |
| Uses: | This antibody is useful for western blot and immunoprecipitation. |
| Application Summary: | IP, WB |
| Storage: | Store at 4C. Do not freeze. |
| General References: | 1. Takemura, H., et al. Defective Mre11-dependent Activation of Chk2 by Ataxia Telangiectasia Mutated in Colorectal Carcinoma Cells in Response to Replication-dependent DNA Double Strand Breaks. J. Biol. Chem. 281(41): 30814-30823 (2006). |