| request information: |
|
| Catalog Code: | NB110-60015 |
| Product Name: | Beta-2-microglobulin Antibody |
| Product Description: | Mouse Monoclonal anti-Beta-2-microglobulin (B2M-01), conjugated FITC |
| Clone: | B2M-01 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Concentration: | 1 mg/ml |
| Immunogen: | Purified human beta2-microglobulin |
| Specificity: | The antibody B2M-01 reacts with beta2-microglobulin (b2M) associated with cell-surface MHC Class I molecules and other membrane antigens as well as with soluble beta2-microglobulin. b2M is a 12 kDa Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes. |
| Cross Reactivity: | Cross-reacts with Human. Does not cross-react with Chicken, Cow, Dog, Mouse or Rabbit. Not yet tested in other species. Weak positive staining was observed in peripheral blood lymphocytes of the monkey Cercopithecus aethiops. |
| Packaging: | 0.1 mg Affinity purified Mouse ascites. |
| Background: | Beta 2 Microglobulin non covalently associates with the 44 kDa alpha chain to form the HLA Class I antigen complex. Human beta 2 Microglobulin associated with HLA Class I antigens are expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Affinity purified |
| Isotype: | IgG2a |
| Host Name: | Mouse |
| Buffer: | PBS, pH 7.4 |
| Application Summary: | flow cytometry / FACS analysis 1/200 |
| Species Summary: | Bv(-), Ca(-), Ch(-), Hu, Mu(-), Rb(-), |
| Alternate Names: | anti-B2M antibody, anti-Beta 2 microglobulin precursor antibody, anti-Beta chain of mhc class 1 proteins antibody, anti-Hdcma22p antibody |
| Package Size: | 0.1 mg |
| Preservative: | 15mM Sodium Azide |
| Conjugate: | FITC |
| General References: | *Hilgert I, Horejsi V, Kristofova H.: The use of murine monoclonal antibody B2M-01 for detection and purification of human beta 2-microglobulin. Folia Biol (Praha). 1984;30(6):369-76. *Khurana M, Traum AZ, Aivado M, Wells MP, Guerrero M, Grall F, Libermann TA, Schachter AD.: Urine proteomic profiling of pediatric nephrotic syndrome. Pediatr Nephrol. 2006 Sep;21(9):1257-65. Epub 2006 Jun 30. |
order or
more information: | company product webpage |
|