| CatalogCode: | | NB110-59991 |
| ProductName: | | CD163 Antibody |
| Product Description: | | Mouse Monoclonal anti-CD163 (RM3/1) |
| Clone: | | RM3/1 |
| Clonality: | | Monoclonal |
| Immunogen: | | human monocytes |
| CrossReactivity: | | This antibody is reactive against human. |
| Packaging: | | 0.1 mg Affinity purified Mouse ascites. |
| Uses: | | This antibody works in FC. |
| Background: | | CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, Hemoglobin-Haptoglobin Complex Receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kuffer cells, monocytes, subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP) resulting in soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammation diseases. |
| Storage: | | Store at 4C. Do not freeze. |
| Purity: | | Affinity purified |
| Isotype: | | IgG1, k |
| Host_Name: | | Mouse |
| Buffer: | | Phosphate-buffered solution, pH 7.2. |
| ListPrice: | | 295 |
| AppSummary: | | FACS |
| SpeciesSummary: | | Hu |
| ALTnames: | | GHI/61, M130, RM3/1, p155, Hemoglobin/Haptoglobin Complex Receptor, macrophage-associated antigen, ED2(rat), Macrophage marker |
| PackageSize: | | 0.1 mg |
| GeneralRef: | | 1. Roth, J., et al., 1994. Transolantation. 57:127. 2. Van den Heuvel, MM., et al., 1999. J. Leukoc Biol. 66:858. 3. Sulahian, T. H., et al., 2000. Cytokines 12:1312. 4. Fabriek, BO., et al., 2007. J. Neuroimmunol. 187:179. |
| more information: | | company product webpage |
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