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| Catalog Code: | NB110-59961 |
| Product Name: | Rsk4 Antibody |
| Product Description: | Rabbit Monoclonal anti-Rsk4 (EP1982Y) |
| Clone: | EP1982Y |
| Clonality: | Monoclonal |
| ListPrice: | 315 |
| Immunogen: | A synthetic peptide corresponding to residues near the N-terminus of human Rsk 4 was used as an immunogen. |
| Specificity: | This antibody recognizes human Rsk 4. |
| Cross Reactivity: | This antibody is reactive against Human. Not yet tested in other species. |
| Packaging: | 0.1 ml Rabbit ascites. |
| Uses: | This antibody is useful for Western Blot, Immunohistochemistry, Immunocytochemistry, and FACS. |
| Background: | RSK4 is a member of the family of 90-kDa ribosomal S6 kinases (1). These proteins are a class of serine/threonine kinases that are activated in response to various extracellular signals, including growth factors, polypeptide hormones and neurotransmitters (2). RSK4 is most abundantly expressed in brain and kidney. The predicted protein of 746 amino acids shows a high level of homology to three previously isolated members of the human RSK family. RSK2 is involved in Coffin-Lowry syndrome and nonspecific MRX. The localization of RSK4 in the interval that is commonly deleted in mentally retarded males together with the high degree of amino acid identity with RSK2 suggests that RSK4 plays a role in normal neuronal development (3). |
| Storage: | Aliquot and store at -20 °C. |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| Application Summary: | flow cytometry / FACS analysis 1:25, immunohistochemistry 1:50-1:100, Western Blot 1:250-1:500, Immunocytochemistry 1:100-1:250, |
| Species Summary: | Hu, |
| Alternate Names: | Anti-p90-RSK 6 antibody; Anti-ribosomal protein S6 kinase 90kDa polypeptide 6 antibody; Anti-Ribosomal protein S6 kinase alpha-6 antibody; Anti-Ribosomal S6 kinase 4 antibody; Anti-RPS6KA6 antibody; Anti-RSK-4 antibody |
| Package Size: | 0.1 ml |
| Preservative: | 0.01% sodium azide |
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more information: | company product webpage |