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| Catalog Code: | NB110-59934 |
| Product Name: | Prohibitin Antibody |
| Product Description: | Mouse Monoclonal anti-Prohibitin (II-14-10) |
| Clone: | II-14-10 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | BALB/C mice were injected with purified recombinant rat prohibitin protein. |
| Specificity: | This antibody is specific to 30kD protein known as Prohibitin. Prohibitin is an evolutionarily conserved protein located in the innermembrane of mitochondria. Prohibitin shows antiproliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization and tumor suppression. This antibody cross reacts with mouse, rat and pig. |
| Cross Reactivity: | This antibody is reactive against human, mouse, rat and pig. |
| Packaging: | 6 ml IgG purified Mouse ascites. |
| Uses: | This antibody works in IHC, ICC/IF, WB, IHC-P, IHC-Fr. |
| Localization: | Cytoplasmic |
| Background: | Prohibitin is an evolutionarily conserved protein located in the inner membrane of mitochondria. Prohibitin shows antiproliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization and tumor suppression. Prohibitin is also sometimes found in the nucleus in certain cells types and cell states. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | IgG purified |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Buffer: | 1% BSA |
| Application Summary: | immunohistochemistry, immunofluorescence, Western Blot, Immunocytochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen |
| Species Summary: | Hu, Mu, Rt, , |
| Alternate Names: | anti-PHB antibody, anti-prohibitin antibody |
| Package Size: | 6 ml |
| Preservative: | 0.05% Sodium Azide |
| General References: | i) McClung et al. Exp Gerontol 30 (2): 99, 1995. ii) Sato et al. Cancer Res 52: 1643, 1992. iii) Terashima et al. EBMO 13: 3782, 1994. |
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