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| Catalog Code: | NB110-58773 |
| Product Name: | CSN5 Antibody |
| Product Description: | Rabbit Polyclonal anti-CSN5 |
| Clonality: | Polyclonal |
| ListPrice: | 325 |
| Gene ID: | 10987 |
| Concentration: | 1 mg/ml |
| Immunogen: | The epitope recognized by this antibody maps to a region between residues 175 and 225 of human COP9 constitutive photomorphogenic homolog subunit 5 using the numbering given in entry NP_006828.2 (GeneID 10987). |
| Cross Reactivity: | Human. Reactivity with Mouse, zebrafish, and X. tropicalis likely due to sequence homology. |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | Western Blot: 1:5,000 - 1:25,000Other applications not tested |
| Background: | The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Host Name: | Rabbit |
| Buffer: | Tris-citrate/phosphate buffer, pH 7 to 8 |
| Application Summary: | Western Blot |
| Species Summary: | Hu |
| Alternate Names: | anti-CSN5 antibody, anti-JAB1 antibody, anti-SGN5 antibody, anti-MOV-34 antibody, anti-MGC3149 antibody, anti-COPS5 antibody, anti-COP9 signalosome complex subunit 5 antibody, anti-JAB-1 antibody, anti-Jun Activating Domain-Binding Protein antibody, anti-KIC2 antibody, anti-Kip1 C-terminus interacting protein 2 antibody, anti-Sgn5 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.09% Sodium Azide |
| Homology: | Mouse, zebrafish, X. tropicalis |
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more information: | company product webpage |