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| Catalog Code: | NB110-58731 |
| Product Name: | CD50 Antibody |
| Product Description: | Mouse Monoclonal anti-CD50 (MEM-171) |
| Clone: | MEM-171 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Concentration: | 1.0 mg/ml |
| Immunogen: | Human granulocytes |
| Specificity: | The antibody MEM-171 recognizes an epitope in the D2 domain of CD50 (ICAM-3), a 120-130 kDa type I membrane protein (immunoglobulin supergene family) expressed on leukocytes, endothelial cells and Langerhans cells; it is negative on platelets and erythrocytes. |
| Cross Reactivity: | Human |
| Packaging: | 0.1 mg protein A purified Mouse ascites. |
| Background: | CD50 is an intracellular adhesion molecule 3 (ICAM-3). The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | protein A purified |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Buffer: | PBS, pH 7.4 |
| Application Summary: | flow cytometry / FACS analysis , immunoprecipitation , |
| Species Summary: | Hu, |
| Package Size: | 0.1 mg |
| Preservative: | Sodium Azide |
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more information: | company product webpage |