| Catalog Code: | NB110-58360 |
| Product Type: | Primary Antibody |
| Product Name: | Fe65 Antibody |
| List Price: | 275 |
| Clonality: | Polyclonal |
| Gene ID: | 322 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-Fe65 |
| Cross Reactivity: | This antibody reacts with the human and mouse proteins. No other species have been tested. |
| Species Summary: | Hu, Mu |
| Background: | FE65 is a signaling adaptor of APP protein. The FE65/APP complex was shown to translocate into the cell nucleus and regulate gene expression. Genetic studies in mice validated FE65-APP interaction and molecular studies provided evidence on the role of the |
| Alternate Names: | anti-Amyloid beta A4 precursor protein-binding family B member 1 antibody, anti-Fe65 protein antibody, anti-APBB1 antibody, anti-FE65 antibody, anti-RIR antibody, anti-MGC:9072 antibody |
| Immunogen: | Recombinant rat protein expressed in bacteria. |
| Purity: | Affinity purified |
| Buffer: | PBS, 15% glycerol |
| Packaging: | 0.1 ml Affinity purified Rabbit antisera. |
| Package Size: | 0.1 ml |
| Uses: | This antibody is useful in Western Blot and immunoprecipitation. For western blot, a band is seen at ~100 kDa ((calculated MW of 77.2kDa according to NP_001155.1 and 77.0kDa according to NP_663722.1). The observed molecular weight corresponds to earlier f |
| Application Summary: | IP, WB |
| General References: | 1. Zambrano, N., et al. Interaction of the Phosphotyrosine Interaction/Phosphotyrosine Binding-related Domains of FE65 with Wild-type and Mutant Alzheimer's beta-amyloid Precursor Proteins. JBC. 272:6399-405 (1997). [Western Blot, Immunoprecipitation |