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| Catalog Code: | NB110-58346 |
| Product Name: | Spectrin Beta III Antibody |
| Product Description: | Rabbit Polyclonal anti-Spectrin Beta III |
| Clonality: | Polyclonal |
| ListPrice: | 285 |
| Gene ID: | 6712 |
| Concentration: | 1 |
| Immunogen: | The epitope recognized by this antibody maps to a C-terminal region between residue 2300 and 2390 of human spectrin, beta, non-erythrocytic 2 (spinocerebellar ataxia 5 ) using the numbering given in entry NP_008877.1 |
| Cross Reactivity: | This antibody reacts with human. Other species have not been tested. |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for Western blot analysis and immunoprecipitation. Immunohistochemistry on FFPE sections. |
| Background: | Mutations in spectrins are a previously unknown cause of ataxia and neurodegenerative disease that affect membrane proteins involved in glutamate signaling. Spectrin-beta IIIs have been recognized as ataxia disease genes and their mutations cause spinocerebellar ataxia type 5 (SCA5). |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Host Name: | Rabbit |
| Buffer: | Tris-citrate/phosphate buffer, pH 7 to 8 |
| Application Summary: | immunohistochemistry 10-20 ug/ml, immunoprecipitation 2 to 5 ug/mg lysate, Western Blot 1:2000-1:10000 |
| Species Summary: | Hu, Mu, Rt, |
| Alternate Names: | Anti-SPTBN2 antibody, anti-SPTBN-2 antibody, anti-spectrin antibody, anti-non-erythroid beta chain 2 antibody, anti-Beta-III spectrin antibody, anti-SCA5 antibody, anti-SCA-5 antibody, anti-spinocerebellar ataxia 5 antibody, anti-KIAA0302 antibody |
| Package Size: | 0.1 ml |
| Preservative: | 0.09% Sodium Azide |
| Homology: | 100% with human, mouse, and rat protein. |
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