| CatalogCode: | NB110-57421 |
| ProductName: | PLAP Antibody |
| Product Description: | Rabbit Monoclonal anti-PLAP (Y102) |
| Clone: | Y102 |
| Clonality: | Monoclonal |
| Specificity: | A synthetic peptide corresponding to residues near the N-term of human PLAP was used as immunogen. |
| CrossReactivity: | Reacts in human. Does not react in mouse or rat. Not tested in other species. |
| Packaging: | 0.1 ml |
| Uses: | WB: 1:1,000IHC: 1:50-100ICC: 1:50 |
| Background: | Phospholipase A2 activator protein (PLAP), activates PLA2 (phospholipase A2 enzyme) and is an important mediator of eicosanoid generation. Also known as a pro-inflammatory agent, PLAP has been found in inflamed tissues and synovial fluid from patients with rheumatoid arthritis. As such, it is believed to play an important role in the regulation of inflammatory diseases. The formation of PLAP can be stimulated by IL-1 beta and TNF-alpha (1-2). |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| ListPrice: | 325 |
| AppSummary: | IHC, WB, ICC |
| SpeciesSummary: | Hu, Mu(-), Rt(-) |
| ALTnames: | Glycerophosphatase antibody |
| PackageSize: | 0.1 ml |
| GeneralRef: | 1. Clark, M. A., T. M. Conway, R. G. L. Shorr, and S. T. Crooke. 1987. J. Biol. Chem. 262:4402-4406. 2. Chopra, A. K.; Ribardo, D. A.; Wood, T. G.; Prusak, D. J.; Xu, X.-J.; Peterson, J. W. : Biochim. Biophys. Acta 1444: 125-130, 1999. |
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