| Catalog Code: | NB110-57350 |
| Product Type: | Primary Antibody |
| Product Name: | P13-kinase p85 subunit alpha Antibody |
| List Price: | 325 |
| Clonality: | Monoclonal |
| Gene ID: | 5062 |
| Host: | Rabbit |
| Clone: | EP380Y |
| Isotype: | IgG |
| Product Description: | Rabbit Monoclonal anti-P13-kinase p85 subunit alpha (EP380Y) |
| Cross Reactivity: | Reacts in human and rat. Does not react in mouse. Not tested in other species. |
| Species Summary: | Hu, Mu(-), Rt |
| Background: | PI3-Kinases (PI3-Ks) are a family of lipid kinases that are implicated in signal transduction. PI3-K consists of two subunits; the regulatory subunit p85 and the catalytic subunit p110 (1-2). In quiescent cells p85 maintains p110 in a low activity state. |
| Alternate Names: | # GRB1 antibody # p50 alpha antibody # p55 alpha antibody # p85 alpha antibody # Phosphatidylinositol 3 kinase associated p85 alpha antibody # Phosphatidylinositol 3 kinase regulatory 1 antibody # Phosphatidylinositol 3 kinase regulatory alpha subunit ant |
| Specificity: | A synthetic peptide corresponding to residues in the C-term of human PI3-K 85 alpha was used as an immunogen. |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| Packaging: | .1 ml Rabbit ascites. |
| Package Size: | .1 ml |
| Uses: | WB: 1:500-2,000 IHC: 1:100-250 ICC: 1:250-500 Flow Cytometry: 1:60 IP: 1:50 |
| Application Summary: | FACS, IHC, IP, WB, ICC |
| General References: | 1. Otsu et al. (1992) Cell 65, 91-104 2. Hiles et al. (1991) Cell 70, 419-429 3. Inukai et al. (1997) J. Biol. Chem. 272, 7873-7882 4. Klippel, A., J. A. Escobedo, Q. Hu, and L. T. Williams. Mol. Cell. Biol. 13:5560-5566.5. Jain, S. K., W. Y. Langdon, and |
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