| Catalog Code: | NB110-57275 |
| Product Type: | Primary Antibody |
| Product Name: | Phospho NPM (pT199) Antibody |
| List Price: | 325 |
| Clonality: | Monoclonal |
| Gene ID: | 4869 |
| Host: | Rabbit |
| Clone: | EP1857Y |
| Isotype: | IgG |
| Product Description: | Rabbit Monoclonal anti-Phospho NPM (pT199) (EP1857Y) [Thr199] |
| Phosphorylated: | Thr199 |
| Cross Reactivity: | Reacts in human. Does not react in mouse or rat. Not tested in other species. |
| Species Summary: | Hu, Mu(-), Rt(-) |
| Background: | Nucleophosmin (NPM), a nucleocytoplasmic shuttling protein with prominent nucleolar localization, regulates the ARF-p53 tumor-suppressor pathway. Translocations involving the NPM gene cause cytoplasmic dislocation of the NPM protein (1). NPM is a major nu |
| Specificity: | A phospho-specific peptide corresponding to residues surrounding Theonine 199 was used as an immunogen. This antibody recognizes proteins phosphorylated at T199. |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| Package Size: | .1 ml |
| Application Summary: | IHC, IP, WB, ICC |
| General References: | 1. Falilni B, et al. N Engl J Med 352(3):254-66, 2005 2. Chan PK, et al. Nucleic Acids Res 25(6):1225-32, 19973. Yoneda-Kato N, et al. Oncogene 12(2):265-75, 1996 |
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