| Catalog Code: | NB110-57274 |
| Product Type: | Primary Antibody |
| Product Name: | NPM (N-term) Antibody |
| List Price: | 325 |
| Clonality: | Monoclonal |
| Gene ID: | 4869 |
| Host: | Rabbit |
| Clone: | EP1848Y |
| Isotype: | IgG |
| Product Description: | Rabbit Monoclonal anti-NPM (N-term) (EP1848Y) |
| Cross Reactivity: | Reacts in human. Does not react in mouse or rat. Not tested in other species. |
| Species Summary: | Hu, Mu(-), Rt(-) |
| Background: | Nucleophosmin (NPM), a nucleocytoplasmic shuttling protein with prominent nucleolar localization, regulates the ARF-p53 tumor-suppressor pathway. Translocations involving the NPM gene cause cytoplasmic dislocation of the NPM protein (1). NPM is a major nu |
| Alternate Names: | anti-B23 antibody, anti-MGC104254 antibody, anti-NO38 antibody, anti-NPM 1 antibody, anti-NPM antibody, anti-NPM1 antibody, anti-Nucleolar Phosphoprotein B23 antibody, anti-Nucleolar protein NO38 antibody, anti-Nucleophosmin/B23.2 antibody, anti-Nucleopla |
| Specificity: | A synthetic peptide corresponding to residues on the N-terminus of human NPM was used as an immunogen. |
| Purity: | Ascites |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| Packaging: | 0.1 ml Ascites Rabbit ascites. |
| Package Size: | 0.1 ml |
| Uses: | This antibody is useful for Western blot, flow cytometry/FACS analysis, immunoprecipitation, and immunohistochemitsry on paraffin-embedded tissue |
| Application Summary: | FACS, IP, WB, IHC-P |
| General References: | 1. Falilni B, et al. N Engl J Med 352(3):254-66, 2005 2. Chan PK, et al. Nucleic Acids Res 25(6):1225-32, 19973. Yoneda-Kato N, et al. Oncogene 12(2):265-75, 1996 |
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