| CatalogCode: | NB110-57270 |
| ProductName: | NGF-Beta Antibody |
| Product Description: | Rabbit Monoclonal anti-NGF-Beta (EP1320Y) |
| Clone: | EP1320Y |
| Clonality: | Monoclonal |
| Immunogen: | Synthetic peptide corresponding to residues near the C-terminus of human NGF-ß |
| Specificity: | A synthetic peptide corresponding to residues near the C-terminus of human NGF-â was used as an immunogen. |
| CrossReactivity: | Reacts in human, mouse, and rat. Not tested in other species. |
| Packaging: | 0.1 ml Tissue culture supernatant Rabbit ascites. |
| Uses: | WB: 1:500IHC: 1:50 - 100ICC: 1:100 -250 |
| Background: | Nerve growth factor (NGF) stimulates division and differentiation of sympathetic and embryonic sensory neurons. NGF is thought to have a profound effect on the development and maintenance of sympathetic and embryonic sensory neurons (1). NGF activity isolated from the male mouse submaxillary gland (MSG) consists of three types of subunits, alpha, beta and gamma, which specifically interact to form a 7S, approximately 130,000-molecular weight (Mr) complex. The 7S complex contains two identical 118-amino acid beta-chains, which are solely responsible for the nerve growth-stimulating activity of NGF. While NGF is found in almost all vertebrates, most research has focused on murine NGF, as the mouse male submaxillary gland contains higher levels of this polypeptide than other tissues (2). |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Tissue culture supernatant |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| ListPrice: | 325 |
| AppSummary: | IHC, WB, ICC |
| SpeciesSummary: | Hu, Mu, Rt |
| ALTnames: | anti-Beta nerve growth factor precursor antibody, anti-Beta NGF antibody, anti-HSAN5 antibody, anti-Nerve growth factor beta polypeptide antibody, anti-NGF antibody, anti-NGFB antibody |
| PackageSize: | 0.1 ml |
| GeneralRef: | 1. Levi-Montalcini R. Nature 237(4819):1154-62, 1997. 2. Ullrich A, et al. Nature 303(5920):821-5, 1983. |
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