| request information: |
|
| Catalog Code: | NB110-57269 |
| Product Name: | SMAD1 Antibody |
| Product Description: | Rabbit Polyclonal anti-SMAD1 |
| Clonality: | Polyclonal |
| ListPrice: | 345 |
| Concentration: | 0.5 mg/ml |
| Immunogen: | Synthetic peptide corresponding to amino acid residues around 253 of human Smad1. |
| Specificity: | The antibody recognizes ~60 kDa human Smad1. Reactivity to other species has not been tested. |
| Packaging: | 0.1 mg Immunogen affinity purified Rabbit antisera. |
| Uses: | Optimal dilutions should be determined by researcher. |
| Background: | Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of TGFbeta/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF-beta and activin-mediated growth modulation. Smad4 has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFbeta signaling by interfering with TGFbeta-mediated phosphorylation of other Smad family members. |
| Purity: | Immunogen affinity purified |
| Host Name: | Rabbit |
| Buffer: | phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA |
| Application Summary: | Western Blot 1 ug/ml |
| Species Summary: | Hu, |
| Package Size: | 0.1 mg |
| Preservative: | 0.02% sodium azide |
order or
more information: | company product webpage |