| CatalogCode: | NB110-57124 |
| ProductName: | Interleukin-6 Antibody |
| Product Description: | Rabbit Monoclonal anti-Interleukin-6 (E457) |
| Clone: | E457 |
| Clonality: | Monoclonal |
| Specificity: | A recombinant human IL-6 protein was used as immunogen. |
| CrossReactivity: | Reacts in human. Does not react in mouse or rat. Not tested in other species. |
| Packaging: | 0.1 ml |
| Uses: | WB: 1:10,000 |
| Background: | Interleukin-6 (IL-6) is a multifunctional cytokine with a wide variety of biological functions. IL-6 is implicated in the final differentiation of B-cells into immunoglobulin-secreting cells (1), myeloma and plasmacytoma growth (2), nerve cell differentiation, and activation of hepatocytes and mitogen-stimulated helper T cells (3). Upon activation, IL-6 induces at least three major signaling pathways: JAK/STAT, PI-3 kinase and MAPK (4,5). |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| ListPrice: | 325 |
| AppSummary: | WB |
| SpeciesSummary: | Hu, Mu(-), Rt(-) |
| ALTnames: | B cell stimulatory factor 2 antibody BSF 2 antibody BSF2 antibody CDF antibody CTL differentiation factor antibody Cytotoxic T cell differentiation factor antibody Hepatocyte stimulating factor antibody HGF antibody HPGF antibody HSF antibody Hybridoma growth factor antibody Hybridoma plasmacytoma growth factor antibody IFNB2 antibody IL 6 antibody IL6 protein antibody Interferon beta 2 antibody Interleukin 6 antibody Interleukin6 antibody |
| PackageSize: | 0.1 ml |
| GeneralRef: | 1. Hirano, T., et al. Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin. Nature 324: 73-6 (1986). 2. Brakenhoff, J.P., et al. Molecular cloning and expression of hybridoma growth factor in Escherichia coli. J Immunol. 139: 4116-21 (1987). 3. Wong, G.G., et al. Interleukin 6: identification as a hematopoietic colony-stimulating factor. Behring Inst Mitt. 83: 40-7 (1988). 4. Taniguchi, T. Cytokine signaling through nonreceptor protein tyrosine kinases. Science 268: 251-255 (1995). 5. Boulton, T.G., et al. Ciliary neurotrophic factor/leukemia inhibitory factor/interleukin 6/oncostatin M family of cytokines induces tyrosine phosphorylation of a common set of proteins overlapping those induced by other cytokines and growth factors. J. Biol. Chem. 269: 11648-11655 (1994). |
order or
more information: | company product webpage |
| request information: |
|
|