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| Catalog Code: | NB110-57119 |
| Product Name: | IL-8 Antibody |
| Product Description: | Rabbit Monoclonal anti-IL-8 (EP117Y) |
| Clone: | EP117Y |
| Clonality: | Monoclonal |
| ListPrice: | 325 |
| Specificity: | A synthetic peptide corresponding to residues in human IL-8 was used as an immunogen. |
| Cross Reactivity: | Reacts in human. Does not react in mouse or rat. Not tested in other species. |
| Packaging: | 0.1 ml |
| Uses: | WB: 1:50,000 - 100,000 |
| Background: | Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors (1). Interleukin-8 (IL-8) belongs to a family of small, structurally related cytokines similar to platelet factor 4. It is produced by phagocytes and mesenchymal cells exposed to inflammatory stimuli (e.g., interleukin-1 or tumor necrosis factor) and activates neutrophils inducing chemotaxis, exocytosis and the respiratory burst. In vivo, IL-8 elicits a massive neutrophil accumulation at the site of injection (2). It has recently been shown that IL-8, through its effects on the macrophage and endothelial cell, may be involved in the pathogenesis of atherosclerosis (3) |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| Application Summary: | Western Blot |
| Species Summary: | Hu, Mu(-), Rt(-), |
| Alternate Names: | anti-NAP 1 antibody, anti-3 10C antibody, anti-310C antibody, anti-AMCF 1 antibody, anti-AMCF1 antibody, anti-b ENAP antibody, anti-Beta thromboglobulin like protein antibody, anti-CXC chemokine ligand 8 antibody, anti-CXCL 8 antibody, anti-CXCL8 antibody, anti-Emoctakin antibody, anti-GCP 1 antibody, anti-GCP1 antibody, anti-Granulocyte chemotactic protein 1 antibody, anti-IL 8 antibody, anti-Inteleukin 8 antibody, anti-Interleukin8 antibody, anti-K 60 antibody, anti-K60 antibody, anti-LECT antibody, anti-LUCT antibody, anti-Lymphocyte derived neutrophil activating factor antibody, anti-LYNAP antibody, anti-MDNCF a antibody, anti-MDNCF alpha antibody, anti-MDNCF antibody, anti-MONAP antibody, anti-Monocyte derived neutrophil activating peptide antibody, anti-Monocyte derived neutrophil activating protein antibody, anti-Monocyte derived neutrophil chemotactic factor antibody, anti-NAF antibody, anti-NAP1 antibody, anti-Neutrophil activating factor antibody, anti-Neutrophil activating peptide 1 antibody, anti-Neutrophil activating protein 1 antibody, anti-Protein 3 10C antibody, anti-SCYB 8 antibody, anti-SCYB8 antibody, anti-T cell chemotactic factor antibody, anti-TSG 1 antibody, anti-TSG1 antibody |
| Package Size: | 0.1 ml |
| Preservative: | 0.01% sodium azide |
| General References: | 1. Belperio JA, et al. J Leukoc Biol 68(1):1-8, 2000 2. Baggiolini M, et al. FEBS Lett. 307(1):97-101, 1992 3. Bruun JM, et al. J Clin Endocrinol Metab 86(3):1267-73 2001 |
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