| CatalogCode: | | NB110-57010 |
| ProductName: | | Glycogen Synthase (C-term) Antibody |
| Product Description: | | Rabbit Monoclonal anti-Glycogen Synthase (C-term) (EP817Y) |
| Clone: | | EP817Y |
| Clonality: | | Monoclonal |
| Immunogen: | | Synthetic peptide corresponding to residues in the C-terminus of Human Glycogen Synthase. |
| Specificity: | | A synthetic peptide corresponding to residues in the C-terminus of the human glycogen synthase was used as immunogen. |
| CrossReactivity: | | Reacts in human, mouse, and rat. Not tested in other species. |
| Packaging: | | 0.1 ml protein A purified Rabbit ascites. |
| Uses: | | WB: 1:10,000-50,000IHC: 1:250-500ICC: 1:250-500Flow Cytometry: 1:50IP: 1:50 |
| Background: | | Glycogen synthase is an enzyme of the transferase class that catalyses the reaction of UDP-glucose and (1,4-á-D-glucosyl)n to yield UDP and (1,4-á-D-glucosyl)n+1 (1-2). This tetrameric enzyme is the rate-limiting step for glycogen synthesis (3). Glycogen concentrations are regulated by the complementary activities of glycogen phosphorylase and glycogen synthase. Glycogen synthase activity is regulated by phosphorylation of serine residues and by insulin stimulation (4). Glycogen synthase is known to have two forms; the unphosphorylated and most active form, synthase-a, and the phosphorylated glucose-6-phosphate-dependent form, synthase-b. |
| Storage: | | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | | protein A purified |
| Isotype: | | IgG |
| Host_Name: | | Rabbit |
| Buffer: | | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| ListPrice: | | 325 |
| AppSummary: | | FACS, IHC, IP, WB, ICC |
| SpeciesSummary: | | Hu, Mu, Rt |
| ALTnames: | | anti-Glycogen antibody, anti-Glycogen synthase 1 (muscle) antibody, anti-Glycogen synthase 1 antibody, anti-Glycogen synthase1 antibody, anti-GSY antibody, anti-GYS 1 antibody, anti-GYS antibody, anti-GYS1 antibody, anti-Starchsynthase muscle antibody |
| PackageSize: | | 0.1 ml |
| GeneralRef: | | 1. Browner, M. F.; Nakano, K.; Bang, A. G.; Fletterick, R. J. : Proc. Nat. Acad. Sci. 86: 1443-1447, 1989. 2. Skurat, A., and Roach, P. J. (1996) in Diabetes Mellitus pp. 213-222, 3. Hardy, T. A., and Roach, P. J. (1993) J. Biol. Chem. 268, 23799-23805 4. Skurat, A. V., Wang, Y. & Roach, P. J. (1994) J. Biol. Chem. 269, 25534-25542 |
| more information: | | company product webpage |
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