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| Catalog Code: | NB110-57008 |
| Product Name: | GluR3 Antibody |
| Product Description: | Rabbit Monoclonal anti-GluR3 (EP813Y) |
| Clone: | EP813Y |
| Clonality: | Monoclonal |
| ListPrice: | 325 |
| Specificity: | A synthetic peptide corresponding to residues in the human Glutamate receptor type 3 was used as an immunogen. |
| Cross Reactivity: | Reacts in human and mouse. Does not react in rat. Not tested in other species. |
| Packaging: | 0.1 ml |
| Uses: | WB: 1: 1,000-5,000IHC: 1:50-100ICC: 1:50-100IP: 1:50 |
| Background: | Glutamate receptor type 3 (GluR3) is one of the four subunits of á-amino-5-hydroxy-3-methyl-4-isoxazole propionic acid (AMPA) receptor. AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the central nervous system (CNS). AMPA receptors are composed of four types of subunits, designated as GluR1, GluR2, GluR3, and GluR4 (alternatively called GluRA-D), which combine to form tetramers. The complex composed of GluR2 and GluR3 is one of the two predominant forms in the adult hippocampus. All four GluRs interact with specific cytoplasmic protein through their C-terminal tails. Although in contrast to GluR1 and GluR4, GluR3 and GluR2 have a short C-terminal tail. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| Application Summary: | immunohistochemistry, immunoprecipitation, Western Blot, Immunocytochemistry |
| Species Summary: | Hu, Mu, Rt(-), |
| Alternate Names: | anti-GLUR3 antibody, anti-Glutamate receptor metabotropic 3 antibody, anti-GPRC1C antibody, anti-GRM 3 antibody, anti-GRM3 antibody, anti-Metabotropic glutamate receptor 3 antibody, anti-Metabotropic glutamate receptor 3 precursor antibody, anti-mGlu 3 antibody, anti-MGlu3 antibody, anti-MGLUR 3 antibody, anti-MGLUR3 antibody |
| Package Size: | 0.1 ml |
| Preservative: | 0.01% sodium azide |
| General References: | 1. Han, J.; Lee, J.-D.; Jiang, Y.; Li, Z.; Feng, L.; Ulevitch, R. J. : J. Biol. Chem. 271: 2886-2891, 1996. 2. Seger, R.; Krebs, E. G. : FASEB J. 9: 726-735, 1995. 3. Bernd Stein, Helen Brady, Maria X. Yang , David B. Young, Miguel S. Barbosa, Volume 271, Number 19, Issue of May 10, 1996 pp. 11427-11433 4. Fujishiro et al. J. Biol. Chem., Vol. 276, Issue 23, 19800-19806, 2001 |
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