| CatalogCode: | NB110-57006 |
| ProductName: | GluR2 Antibody |
| Product Description: | Rabbit Monoclonal anti-GluR2 (EP966Y) |
| Clone: | EP966Y |
| Clonality: | Monoclonal |
| Immunogen: | Synthetic peptide corresponding to residues near the N terminus of human GluR2. |
| Specificity: | A synthetic peptide corresponding to a residue near N-term of human Glutamate receptor type 2 was used as immunogen. |
| CrossReactivity: | Reacts in human, mouse, and rat. Not tested in other species. |
| Packaging: | 0.1 ml Rabbit ascites. |
| Background: | Glutamate receptor type 2 (GluR2) is one of the four subunits of á-amino-5-hydroxy-3-methyl-4-isoxazole propionic acid (AMPA) receptor. AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the central nervous system (CNS (1). AMPA receptors are composed of four types of subunits, designated as GluR1, GluR2, GluR3, and GluR4 (alternatively called GluRA-D), which combine to form tetramers (2). The complex comprising of GluR2 and GluR3 is one of the two predominant forms in the adult hippocampus. All four GluRs interact with specific cytoplasmic protein through their C-terminal tails. Although in contrast to GluR1 and GluR4, GluR3 and GluR2 have a short C-terminal tail (3). |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Ascites |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.18 M NaCl, 40% Glycerol, 0.25 mM EDTA, 25 mM Citric Acid, and 0.5% BS |
| ListPrice: | 325 |
| AppSummary: | FACS, IP, WB |
| SpeciesSummary: | Hu, Mu, Rt |
| ALTnames: | anti-AMPA 2 antibody, anti-AMPA selective glutamate receptor 2 antibody, anti-AMPA2 antibody, anti-Glu R2 antibody, anti-Glu RB antibody, anti-GluR 2 antibody, anti-GluR B antibody, anti-GluR B flop antibody, anti-GluR K2 antibody, anti-GluRB antibody, anti-Glutamate receptor 2 antibody, anti-Glutamate receptor ionotropic AMPA 2 antibody, anti-Glutamate receptor ionotropic AMPA2 antibody, anti-Gria 2 antibody, anti-Gria2 antibody, anti-HBGR 2 antibody, anti-HBGR2 antibody |
| PackageSize: | 0.1 ml |
| GeneralRef: | 1. Pellegrini DE, et al. Proc Natl Acad Sci 88:4157-4161 2001. 2. Boehm J, et al. Biochem Soc Trans 33:1334-1336. 2005. 3. Dingledine R, et al. Pharm Review 51:7-62. 1999. |
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