| Catalog Code: | NB110-57000 |
| Product Type: | Primary Antibody |
| Product Name: | Phospho-Gab1 (pY627) Antibody |
| List Price: | 325 |
| Clonality: | Monoclonal |
| Gene ID: | 2549 |
| Host: | Rabbit |
| Clone: | E128 |
| Isotype: | IgG |
| Product Description: | Rabbit Monoclonal anti-Phospho-Gab1 (pY627) (E128) [Tyr627] |
| Phosphorylated: | Tyr627 |
| Cross Reactivity: | Reacts in human. Does not react in mouse or rat. Not tested in other species. |
| Species Summary: | Hu, Mu(-), Rt(-) |
| Background: | Gab1 (Grb2-associated binder-1) is an adaptor protein that serves to activate numerous intracellular signaling pathways via its interaction with receptor tyrosine kinases (RTKs). Gab1 is a substrate of various RTKs, including EGFR, insulin receptor, cytok |
| Alternate Names: | anti-Gab1 antibody, anti-GRB 2 associated binder 1 antibody, anti-GRB 2 associated binding protein 1 antibody, anti-GRB2 associated binder 1 antibody, anti-GRB2 associated binding protein 1 antibody, anti-GRB2 associated binding protein 1 isoform a antibo |
| Specificity: | A synthetic phospho-peptide corresponding to residues surrounding Tyr627 of human Gab1 was used as immunogen. The antibody only detects Gab1 phosphorylated on Tyrosine 627. |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| Package Size: | .1 ml |
| Uses: | WB: 1:1000 IHC: 1:250IP: 1:50 |
| Application Summary: | IHC, IP, WB |
|