| Catalog Code: | NB110-56996 |
| Product Type: | Primary Antibody |
| Product Name: | mTOR/FRAP Antibody |
| List Price: | 325 |
| Clonality: | Monoclonal |
| Gene ID: | 2475 |
| Host: | Rabbit |
| Clone: | Y391 |
| Isotype: | IgG |
| Product Description: | Rabbit Monoclonal anti-mTOR/FRAP (Y391) |
| Cross Reactivity: | Reacts in human, mouse, and rat. Not tested in other species. |
| Species Summary: | Hu, Mu, Rt |
| Background: | The mammalian target of rapamycin (mTOR) is a major effector of cell growth and proliferation via the regulation of protein synthesis. mTOR is composed of an N-term; 20 tandem repeats- HEAT which are implicated in protein-protein interactions and a C-term |
| Alternate Names: | anti-FK506 binding protein12-rapamycin associated protein 1 antibody, anti-FK506 binding protein12-rapamycin associated protein 2 antibody, anti-FKBP12 rapamycin complex associated protein antibody, anti-FLJ44809 antibody, anti-FRAP antibody, anti-FRAP1 a |
| Specificity: | A synthetic peptide corresponding to residues near the C-term of PI3K/PI4K domain of human mTOR/FRAP was used as an immunogen |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| Package Size: | .1 ml |
| Uses: | WB: 1:1,000-2,000 IHC: 1:250-500 ICC: 1:50-100 Flow Cytometry: 1: 80IP: 1:50 |
| Application Summary: | FACS, IHC, IP, WB, ICC |
| General References: | Hay, N.; Sonenberg, N. :Genes Dev. 18: 1926-1945, 2004. |
|