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| Catalog Code: | NB110-56978 |
| Product Name: | p44 MAPK (Erk1) Antibody |
| Product Description: | Rabbit Monoclonal anti-p44 MAPK (Erk1) (Y71) |
| Clone: | Y71 |
| Clonality: | Monoclonal |
| ListPrice: | 325 |
| Immunogen: | A synthetic peptide corresponding to residues in C-terminus of human Erk1 |
| Specificity: | This antibody is specific to the p44 MAPK (Erk1) protien. |
| Cross Reactivity: | This antibody reacts with human, mouse, and rat. Other species have not yet been tested. |
| Packaging: | 0.1 ml IgG purified Rabbit ascites. |
| Uses: | This antibody is useful for Wester Blot (Predicted molecular weight: 43 kDa). |
| Background: | p44 MAP Kinase (Erk1) is a member of a family of mitogen-activated protein kinases that participate in diverse cellular functions, including the regulation of cell growth and differentiation (1,2). Erk1 regulates meiosis and mitosis by phosphorylating a number of transcription factors such as ELK-1. Activation of Erk1 occurs through phosphorylation of threonine 202 and tyrosine 204 (of human MAP kinase) (3). Erk1 is also known to autophosphorylate on tyrosine (3). |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | IgG purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | Constituents: 40% Glycerol, 0.05% BSA, 0.15M Sodium chloride, 50mM Tris glycine. pH 7.4 |
| Application Summary: | Western Blot 1/1000 |
| Species Summary: | Hu, Mu, Rt, |
| Alternate Names: | anti-ERK1 antibody, anti-ERT 2 antibody, anti-ERT2 antibody, anti-Extracellular Signal Regulated Kinase 1 antibody, anti-Extracellular signal related kinase 1 antibody, anti-HGNC6877 antibody, anti-HS44KDAP antibody, anti-HUMKER1A antibody, anti-Insulin Stimulated MAP2 Kinase antibody, anti-MAP kinase 1 antibody, anti-MAP Kinase antibody, anti-MAPK 1 antibody, anti-MAPK 3 antibody, anti-MAPK1 antibody, anti-MAPK3 antibody, anti-MGC20180 antibody, anti-Microtubule Associated Protein 2 Kinase antibody, anti-Mitogen Activated Protein Kinase 3 antibody, anti-p44 ERK1 antibody, anti-p44 MAPK antibody, anti-P44ERK1 antibody, anti-P44MAPK antibody, anti-PRKM 3 antibody, anti-PRKM3 antibody, anti-Protein Kinase Mitogen Activated 3 antibody |
| Package Size: | 0.1 ml |
| Preservative: | 0.01% Sodium Azide |
| General References: | 1. Charest, D.L, et al. Molecular cloning, expression, and characterization of the human mitogen-activated protein kinase p44erk1. Mol Cell Biol. 13: 4679-90 (1993). 2. Marshall, C.J. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80: 179-185 (1995). 3. Payne, D.M., et al. Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase). EMBO J. 10: 885-892 (1991). |
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