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| Catalog Code: | NB110-56899 |
| Product Name: | Cyclin A2 (C-term) Antibody |
| Product Description: | Rabbit Monoclonal anti-Cyclin A2 (C-term) (Y193) |
| Clone: | Y193 |
| Clonality: | Monoclonal |
| ListPrice: | 325 |
| Specificity: | A synthetic peptide corresponding to residues in the C-term of human Cyclin A2 was used as immunogen. |
| Cross Reactivity: | Reacts in Human. Does not react in Mouse or Rat. Not tested in other species. |
| Packaging: | 0.1 ml Ascites Rabbit ascites. |
| Uses: | WB: 1:1,000 IHC: 1:50-100 ICC: 1:100-250 IP: 1:50 |
| Background: | Cyclin A is a member of the Cyclin A family that can bind and activate Cdc2 and Cdk2 and is involved in the control of mitosis and S phase (1). During S phase, cyclin A forms a complex with Cdk2, the pRB-related protein p107 and E2F (2). Additionally, deregulation of cyclin A expression might contribute to tumor formation (3). The cyclin A family consist of two members, cyclin A1 and cyclin A2, to which cyclin A2 promotes both G1/S and G2/M transition (4). |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Ascites |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| Application Summary: | immunohistochemistry, immunoprecipitation, Western Blot, Immunocytochemistry |
| Species Summary: | Hu, Mu(-), Rt(-), |
| Alternate Names: | anti-CCN 1 antibody, anti-CCN A antibody, anti-CCN A2 antibody, anti-CCN1 antibody, anti-CCNA 2 antibody, anti-CCNA antibody, anti-CCNA2 antibody, anti-Cyca antibody, anti-Cyclin A antibody, anti-CyclinA antibody, anti-CyclinA2 antibody |
| Package Size: | 0.1 ml |
| Preservative: | 0.01% sodium azide |
| General References: | 1. Pines, J. & Hunter, T. (1990) Nature (London) 346, 760-762. 2. Devoto, S. H., Mudryj, M., Pines, J., Hunter, T. & Nevins, J. R. (1992) Cell 68, 167-176. 3. Wang, J., Zindy, F., Chenivesse, X., Lamas, E., Henglein, B. & Brechot, C. (1992) Oncogene 7, 1653-1656. 4. Pagano, M.; Pepperkok, R.; Verde, F.; Ansorge, W.; Draetta, G. EMBO J. 11: 961-971, 1992. |
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