| CatalogCode: | NB110-55683 |
| ProductName: | CKR9/CCR9 (N-term) Antibody |
| Product Description: | Rabbit Monoclonal anti-CKR9/CCR9 (N-term) (E99) |
| Clone: | E99 |
| Clonality: | Monoclonal |
| Specificity: | A synthetic peptide corresponding to N-terminal residues (extracellular domain) of human CKR9 was used as immunogen. The antibody does not cross-react with other G-protein coupled receptor 1 family members. |
| CrossReactivity: | Reacts in Human and Mouse. Does not react in Rat. Not tested in other species. |
| Packaging: | 0.1 ml |
| Uses: | WB: 1:500ICC: 1:250Flow Cytometry: 1:40 |
| Background: | CKR9/CCR9 (C-C chemokine receptor type 9), also designated GPR-9-6, is a G protein-coupled, seven-transmembrane domain receptor protein. It has been found that CKR9/CCR9 is a receptor for the thymus expressed chemokine TECK (1,2). CKR9/CCR9 and TECK are thought to play a specialized role in the immune response because both are highly expressed by T lymphocytes in the small intestine, where they are not in other tissues (2,3). |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| ListPrice: | 325 |
| AppSummary: | FACS, WB, ICC |
| SpeciesSummary: | Hu, Mu, Rt(-) |
| ALTnames: | anti-C C chemokine receptor D6 antibody, C C chemokine receptor type 9 antibody, C C CKR 9 antibody, CC Chemokine receptor CCR10 antibody, CC CKR 9 antibody, CCBP2 antibody, CCCKR9 antibody, CCR 9 antibody, CCR9 antibody, CDw199 antibody, CDw199 antigen antibody, Chemokine C C motif receptor 9 antibody, Chemokine CC Motif Receptor 9 antibody, Chemokine receptor CCR 9 antibody, Chemokine-binding protein D6 antibody, CMKBR9 antibody, G protein coupled receptor 28 antibody, GPR 28 antibody, GPR 9 6 antibody, GPR28 antibody, GPR96 antibody |
| PackageSize: | 0.1 ml |
| GeneralRef: | 1. Zaballos, A., et al. Cutting edge: identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK. J Immunol. 162: 5671-5 (1999). 2. Zabel, B.A., et al. Human G protein-coupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis. J Exp Med. 190: 1241-56 (1999). 3. Kunkel, E.J., et al. Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity. J. Exp. Med. 192: 761-768 (2000). |
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