| CatalogCode: | | NB110-55682 |
| ProductName: | | CKR8/CCR8 (Loop 2) Antibody |
| Product Description: | | Rabbit Monoclonal anti-CKR8/CCR8 (Loop 2) (E77) |
| Clone: | | E77 |
| Clonality: | | Monoclonal |
| Specificity: | | A synthetic peptide corresponding to residues in loop2 extracellular domain of human CKR8 was used as immunogen. The antibody does not cross-react with other G-protein coupled receptor 1 family members. |
| CrossReactivity: | | Reacts in Human and Rat. Does not react in Mouse. Not tested in other species. |
| Packaging: | | 0.1 ml |
| Uses: | | WB: 1:2,000ICC: 1:250Flow Cytometry: 1:20IP: 1:25 |
| Background: | | CKR8/CCR8, or C-C chemokine receptor type 8, is a G protein-coupled, seven-transmembrane domain receptor protein. Chemokines are key molecules in directing leukocyte migration toward sites of inflammation. The human C-C chemokine I-309 is a monocyte chemoattractant and inhibits apoptosis in thymic cell lines. It has been found that CKR8/CCR8 is a receptor for chemokines SCYA1/I-309, SCYA4/MIP-1-beta, and SCYA17/TARC (1-3). |
| Storage: | | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Isotype: | | IgG |
| Host_Name: | | Rabbit |
| Buffer: | | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| ListPrice: | | 325 |
| AppSummary: | | FACS, IP, WB, ICC |
| SpeciesSummary: | | Hu, Mu(-), Rt |
| ALTnames: | | anti-C C chemokine receptor type 8 antibody, C C CKR 8 antibody, CC chemokine receptor 8 antibody, CC chemokine receptor chemr1 antibody, CC chemokine receptor type 8 antibody, CC CKR 8 antibody, CCR 8 antibody, CCR8 protein antibody, CDw198 antibody, CDw198 antigen antibody, Chemokine (C C motif) receptor 8 antibody Chemokine (C C) receptor 8 antibody, Chemokine (C C) receptor like 2 antibody, Chemokine (CC motif) receptor 8 antibody, Chemokine (CC) receptor 8 antibody, Chemokine (CC) receptor like 1 antibody, Chemokine (CC) receptor like 2 antibody, Chemokine C C motif receptor 8 antibody, Chemokine C C receptor 8 antibody, Chemokine CC motif receptor 8 antibody, Chemokine CC receptor 8 antibody, Chemokine receptor 8 antibody, Chemokine receptor like 1 antibody, CKR L1 antibody, CKRL 1 antibody, CKRL1 antibody, CMKBR 8 antibody, CMKBR L2 antibody, CMKBR8 antibody, CMKBRL 2 antibody, CMKBRL2 antibody, CY 6 antibody, CY6 antibody, GPR CY6 antibody, GPRCY6 antibody, MGC129966 antibody, MGC129973 antibody, TER 1 antibody, TER1 antibody antibody antibody |
| PackageSize: | | 0.1 ml |
| GeneralRef: | | 1. Tiffany, H.L., et al. Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309. J. Exp Med. 186: 165-70 (1997). 2. Goya, I., et al. Identification of CCR8 as the specific receptor for the human beta-chemokine I-309: cloning and molecular characterization of murine CCR8 as the receptor for TCA-3. J Immunol. 160: 1975-81 (1998). 3. Bernardini, G., et al. Identification of the CC chemokines TARC and macrophage inflammatory protein-1 beta as novel functional ligands for the CCR8 receptor. Eur J Immunol. 28: 582-8 (1998). |
| more information: | | company product webpage |
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