| CatalogCode: | NB110-55681 |
| ProductName: | CKR8/CCR8 (C-term) Antibody |
| Product Description: | Rabbit Monoclonal anti-CKR8/CCR8 (C-term) (E76) |
| Clone: | E76 |
| Clonality: | Monoclonal |
| Specificity: | A synthetic peptide corresponding to residues near C-terminus of human CKR8 was used as immunogen. The antibody does not cross-react with other G-protein coupled receptor 1 family members. |
| CrossReactivity: | Reacts in Human and Mouse. Does not react in Rat. Not tested in other species. |
| Packaging: | 0.1 ml |
| Uses: | WB: 1:500ICC: 1:100 |
| Background: | CKR8/CCR8, or C-C chemokine receptor type 8, is a G protein-coupled, seven-transmembrane domain receptor protein. Chemokines are key molecules in directing leukocyte migration toward sites of inflammation. The human C-C chemokine I-309 is a monocyte chemoattractant and inhibits apoptosis in thymic cell lines. It has been found that CKR8/CCR8 is a receptor for chemokines SCYA1/I-309, SCYA4/MIP-1-beta, and SCYA17/TARC (1-3). |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| ListPrice: | 325 |
| AppSummary: | WB, ICC |
| SpeciesSummary: | Hu, Mu, Rt(-) |
| ALTnames: | anti-C C chemokine receptor type 8 antibody, C C CKR 8 antibody, CC chemokine receptor 8 antibody, CC chemokine receptor chemr1 antibody, CC chemokine receptor type 8 antibody, CC CKR 8 antibody, CCR 8 antibody, CCR8 protein antibody, CDw198 antibody, CDw198 antigen antibody, Chemokine (C C motif) receptor 8 antibody Chemokine (C C) receptor 8 antibody, Chemokine (C C) receptor like 2 antibody, Chemokine (CC motif) receptor 8 antibody, Chemokine (CC) receptor 8 antibody, Chemokine (CC) receptor like 1 antibody, Chemokine (CC) receptor like 2 antibody, Chemokine C C motif receptor 8 antibody, Chemokine C C receptor 8 antibody, Chemokine CC motif receptor 8 antibody, Chemokine CC receptor 8 antibody, Chemokine receptor 8 antibody, Chemokine receptor like 1 antibody, CKR L1 antibody, CKRL 1 antibody, CKRL1 antibody, CMKBR 8 antibody, CMKBR L2 antibody, CMKBR8 antibody, CMKBRL 2 antibody, CMKBRL2 antibody, CY 6 antibody, CY6 antibody, GPR CY6 antibody, GPRCY6 antibody, MGC129966 antibody, MGC129973 antibody, TER 1 antibody, TER1 antibody antibody antibody |
| PackageSize: | 0.1 ml |
| GeneralRef: | 1. Tiffany, H.L., et al. Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309. J. Exp Med. 186: 165-70 (1997). 2. Goya, I., et al. Identification of CCR8 as the specific receptor for the human beta-chemokine I-309: cloning and molecular characterization of murine CCR8 as the receptor for TCA-3. J Immunol. 160: 1975-81 (1998). 3. Bernardini, G., et al. Identification of the CC chemokines TARC and macrophage inflammatory protein-1 beta as novel functional ligands for the CCR8 receptor. Eur J Immunol. 28: 582-8 (1998). |
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