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| Catalog Code: | NB110-55646 |
| Product Name: | Calcitonin Antibody |
| Product Description: | Rabbit Monoclonal anti-Calcitonin (SP17) |
| Clone: | SP17 |
| Clonality: | Monoclonal |
| ListPrice: | 325 |
| Specificity: | A recombinant full length mouse calretinin protein. |
| Cross Reactivity: | Reacts in Human, Mouse, and Rat. Not tested in other species. |
| Packaging: | 0.1 ml |
| Uses: | IHC: 1:200 |
| Background: | Calcitonin (Katacalcin) is a 32 amino acids poly-peptide hormone that is commonly expressed in the parafollicular or C cells in the thyroid gland. It is also synthesized in a wide variety of other tissues, including the lung and intestinal tract (1). Calcitonin is a potent plasma calcium-lowering peptide; it decreases the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Calcitonin staining is used in the identification of C cell proliferative abnormalities, such as C cell hyperplasia and invasive tumors (2). Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors (e.g. medullary thyroid carcinomas). Calcitonin activitiy might be exhibited in amyloid deposits within the tumor. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | Tissue culture supernatant with 0.05% BSA. |
| Application Summary: | immunohistochemistry |
| Species Summary: | Hu, Mu, Rt, |
| Alternate Names: | anti-CALC 1 antibody, anti-CALC A antibody, anti-CALC1 antibody, anti-CALCA antibody, anti-CGRP 1 antibody, anti-CGRP I antibody, anti-CGRP antibody, anti-CGRP1 antibody, anti-CGRPI antibody, anti-CT antibody, anti-Calcitonin related polypeptide alpha antibody, anti-KC antibody, anti-Katacalcin antibody, anti-MGC126648 antibody |
| Package Size: | 0.1 ml |
| Preservative: | 0.1% sodium azide |
| General References: | 1. Copp DH, Nature 27:193:381-382, 1962. 2. Mortensen LS et al. Basic Clin Pharmacol Toxicol. 97(1):22-28, 2005. |
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