| Catalog Code: | NB110-55566 |
| Product Type: | Primary Antibody |
| Product Name: | c-Abl Antibody |
| List Price: | 325 |
| Clonality: | Monoclonal |
| Gene ID: | 25 |
| Host: | Rabbit |
| Clone: | Y421 |
| Isotype: | IgG |
| Product Description: | Rabbit Monoclonal anti-c-Abl (Y421) |
| Cross Reactivity: | Human, Rat. Does not react in Mouse. Not tested in other species. |
| Species Summary: | Hu, Mu(-), Rt |
| Background: | c-Abl is a nonreceptor tyrosine kinase that is located in either the nucleus or the cytplasm depending on the splice isoform (1a and 1b). c-Abl is implicated in cell differentiation, division, adhesion and stress response (2). C-Abl is composed of a catal |
| Alternate Names: | anti-Abelson Murine Leukemia Viral Oncogene Homolog 1 antibody, anti-Abelson murine leukemia viral v abl oncogene homolog 1 antibody, anti-Abl 1 antibody, anti-Abl protein antibody, anti-Abl1 antibody, anti-Bcr/c abl oncogene protein antibody, anti-JTK 7 |
| Specificity: | A synthetic peptide corresponding to residues in the protein kinase domain of human C-Abl was used as an immunogen. This antibody is predicted to detect both isoforms based on sequence analysis. |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| Package Size: | .1 ml |
| Uses: | WB: 1:1,000-2,000 IP: 1:50 |
| Application Summary: | IP, WB |
| General References: | 1. Ben-Neriah, Y., A. Bernards, M. Paskind, G. Q. Daley, and D. Baltimore. 1986. Cell 44:577-586 2. Lee, C. H., Saksela, C., Mirza, U. A., Chait, B. T. & Kuriyan, J. (1996) Cell 85, 931-942. 3. Franz, W. M., Berger, P. & Wang, J. Y. (1989) EMBO J. 8, 137- |
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