| Catalog Code: | NB110-55555 |
| Product Type: | Primary Antibody |
| Product Name: | Bcr (C-term) Antibody |
| List Price: | 325 |
| Clonality: | Monoclonal |
| Gene ID: | 613 |
| Host: | Rabbit |
| Clone: | EP535Y |
| Isotype: | IgG |
| Product Description: | Rabbit Monoclonal anti-Bcr (C-term) (EP535Y) |
| Cross Reactivity: | Human. Does not react in Mouse or Rat. Not tested in other species. |
| Species Summary: | Hu, Mu(-), Rt(-) |
| Background: | The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML) (1-2). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 bin |
| Alternate Names: | anti-BCR 1 antibody, anti-BCR/ABL FUSION GENE INCLUDED antibody, anti-BCR/FGFR1 FUSION GENE INCLUDED antibody, anti-BCR/PDGFRA FUSION GENE INCLUDED antibody, anti-BCR1 antibody, anti-breakpoint cluster region antibody |
| Specificity: | A synthetic peptide corresponding to residues in the C-term of human Bcr was used as immunogen. |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.5% BSA. |
| Package Size: | .1 ml |
| Uses: | WB: 1:2,000-10,000 IHC: 1:50-100 ICC: 1:100-250 Flow Cytometry: 1:20 IP: 1:60 |
| Application Summary: | FACS, IHC, IP, WB, ICC |
| General References: | 1. Clark, S. S., McLaughlin, J., Timmons, M., Pendergast, A. M., Ben-Neriah, Y., Dow, L. W., Crist, W., Rovera, G., Smith, S. D. and Witte, O. N. (1988). Science 239, 775-777 2. Konopka, J. B., Watanabe, S. M. and Witte, O. N. (1984). Cell 37, 1035-1042 3 |
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