| CatalogCode: | NB110-55547 |
| ProductName: | KDR Antibody |
| Product Description: | Rabbit Polyclonal anti-KDR |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide - KLH conjugated. |
| Epitope: | internal domain of human |
| Specificity: | This antibody is specific to the human KDR protein. |
| CrossReactivity: | Human. Other species not tested. |
| Packaging: | 0.05 mg peptide affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for immunohistochemistry. Optimal dilution to be determined by the researcher. |
| Localization: | Type I membrane protein |
| Background: | VEGF receptor 2 is a member of a receptor tyrosine kinase family whose activation plays an essential role in a large number of biological processes such as embryonic development, wound healing, cell proliferation, migration and differentiation. Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues. These sites can be involved in the regulation of kinase activity or serve as binding sites for SH2 and phosphotyrosine binding containing signalling proteins. Phosphorylation of Tyrosines 1054 and 1059 in the activation loop is required for activation of VEGF receptor 2 and its intrinsic tyrosine kinase activity. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | peptide affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Phosphate buffered saline, PH 7.7 |
| ListPrice: | 350 |
| AppSummary: | IHC |
| SpeciesSummary: | Hu |
| ALTnames: | anti-CD309 antibody; anti-EC 2.7.10.1 antibody; anti-FLK1 antibody; anti-KDR antibody; anti-VEGFR antibody; anti-VEGFR-2 antibody; anti-VEGFR2 antibody |
| PackageSize: | 0.05 mg |