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| Catalog Code: | NB110-55533 |
| Product Name: | FLT1 Antibody |
| Product Description: | Rabbit Polyclonal anti-FLT1 |
| Clonality: | Polyclonal |
| ListPrice: | 350 |
| Concentration: | 0.14 mg/ml |
| Immunogen: | Synthetic peptide - KLH conjugated. |
| Epitope: | N-terminal domain of human |
| Specificity: | This antibody is specific to the human FLT1 protein. |
| Cross Reactivity: | Human. Other species not tested. |
| Packaging: | 0.05 mg Immunogen affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for immunohistochemistry. Optimal dilution to be determined by the researcher. |
| Localization: | Type I membrane protein (isoform Flt1) and soluble (isoform SFlt1). |
| Background: | VEGF Receptor 1 (also known as FLT) belongs to the src gene family and shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The protein acts as a receptor for VEGF, VEGFB and PGF. An alternatively spliced form of the gene produces a soluble protein (sFlt1) which binds vascular endothelial growth factor (VEGF) with high affinity. sFlt1 has a higher affinity for VEGF indicating that it may function as an inhibitor in the VEGF response. VEGF Receptor 1 is specifically expressed in most vascular endothelial cells and peripheral blood monocytes. VEGFR 1 is a cell membrane receptor kinase. It has a high affinity receptor for vascular endothelial growth factor and is putatively involved in the growth of endothelial cells and angiogenesis. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Host Name: | Rabbit |
| Buffer: | Phosphate buffered saline, PH 7.7 |
| Application Summary: | immunohistochemistry 5-10 ug/ml |
| Species Summary: | Hu, |
| Alternate Names: | anti-EC 2.7.10.1 antibody; anti-FLT antibody; anti-FLT-1 antibody; anti-FLT1 antibody; anti-FRT antibody; anti-VEGFR-1 antibody; anti-VEGFR1 antibody |
| Package Size: | 0.05 mg |
| Preservative: | 0.1 % sodium azide |
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more information: | company product webpage |