| Catalog Code: | NB110-55491 |
| Product Type: | Primary Antibody |
| Product Name: | Bak Antibody |
| List Price: | 325 |
| Clonality: | Monoclonal |
| Gene ID: | 578 |
| Host: | Rabbit |
| Clone: | Y164 |
| Isotype: | IgG |
| Product Description: | Rabbit Monoclonal anti-Bak (Y164) |
| Cross Reactivity: | Human. Does not react with Mouse or Rat. Not tested in other species. |
| Species Summary: | Hu, Mu(-), Rt(-) |
| Background: | Bak a pro-apoptotic analog to Bax, is a member of the Bcl-2 family of proteins. During mitochondria-regulated programmed cell death, Bak promotes apoptosis by binding Bcl-2 and inhibiting its anti-apoptotic function (1). Upon apoptotic stimulation, Bak tr |
| Alternate Names: | anti-Apoptosis Regulator Bak antibody, anti-BAK 1 antibody, anti-BAK antibody, anti-BAK like antibody, anti-Bak NT antibody, anti-BAK1 antibody, anti-Bcl 2 homologous antagonist/killer antibody, anti-Bcl 2 like 7 protein antibody, anti-Bcl2 homologous ant |
| Specificity: | A synthetic peptide corresponding to residues near the N-term of human Bak was used as immunogen. The antibody does not cross-react with other Bcl-2 members |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| Package Size: | .1 ml |
| Uses: | WB: 1:1,000-5,000 IHC: 1:250-500 ICC: 1:250-500 Flow Cytometry: 1:10 |
| Application Summary: | FACS, IHC, WB, ICC |
| General References: | 1. Greider, C.W., and Blackburn, E.H. (1985). Cell 43, 405-413 2. Feng J, Funk WD, Wang SS, et al. Science 1995; 269:1236-413. Greider, C.W. (1996). Telomere length regulation. Annu. Rev. Biochem. 65, 337-365 |
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