| CatalogCode: | NB110-55476 |
| ProductName: | ATP-citrate lyase Antibody |
| Product Description: | Rabbit Monoclonal anti-ATP-citrate lyase (EP704Y) |
| Clone: | EP704Y |
| Clonality: | Monoclonal |
| Immunogen: | Synthetic peptide corresponding to residues in the C-term of human ATP citrate lyase. |
| Specificity: | A synthetic peptide corresponding to residues in the C-term of human ATP citrate lyase was used as immunogen. |
| CrossReactivity: | Human, Mouse Rat. Not tested in other species. |
| Packaging: | 0.1 ml IgG purified Rabbit ascites. |
| Uses: | WB: 1:1,000-5,000Flow Cytometry: 1: 30IP: 1:50 |
| Background: | ATP citrate lyase (ACL) is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer of four identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. One of these products, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. NDPK has been found to phosphorylate ACL and insulin to increase phosphorylation of ACL (2). |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | IgG purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| ListPrice: | 325 |
| AppSummary: | FACS, IP, WB |
| SpeciesSummary: | Hu, Mu, Rt |
| ALTnames: | anti-ACL antibody, anti-ATP citrate (pro-S) lyase antibody, anti-ATP citrate synthase antibody, anti-ACL antibody, anti-ATP citrate (pro-S) lyase antibody, anti-ATP citrate lyase antibody, anti-ATP citrate synthase antibody, anti-Citrate cleavage enzyme antibody, anti-EC 2.3.3.8 antibody, anti-Citrate cleavage enzyme antibody, anti-EC 2.3.3.8 antibody |
| PackageSize: | 0.1 ml |
| GeneralRef: | 1. Elshourbagy et al. Europ. J. Biochem. 204: 491-499, 1992. 2. Benjamin, W. B., and Singer, I. (1974) Biochim. Biophys. Acta 251, 28-42 |
|