| CatalogCode: | NB110-55290SS |
| ProductName: | Opa1 Antibody |
| Product Description: | Rabbit Polyclonal anti-Opa1 |
| Clonality: | Polyclonal |
| Immunogen: | A synthetic peptide made to an internal region within residues 500-600 of the human protein. [Swiss-Prot# O60313] |
| CrossReactivity: | This antibody reacts with the human protein. It has not been tested against any other species. |
| Packaging: | 0.025 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for Western blot analysis where a band is seen at ~111 kDa. |
| Localization: | Mitochondrion; mitochondrial inner membrane; single-pass membrane protien. Mitochondrion; mitochondrial intermembrane space. |
| Background: | This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Eight transcript variants encoding different isoforms, resulting from alternative splicing of exon 4 and two novel exons named 4b and 5b, have been reported for this gene. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Tris-glycine, 150mM NaCl |
| ListPrice: | 100 |
| AppSummary: | IHC, WB |
| SpeciesSummary: | Hu, Mu |
| ALTnames: | Anti-Dynamin-like 120 kDa protein antibody; Anti-Optic atrophy protein 1 antibody; Anti-Mgm1 (homolog) antibody |
| PackageSize: | 0.025 ml |
| Homology: | 100% human, mouse, rat, and chicken |