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| Catalog Code: | NB110-55237 |
| Product Name: | DRP1 Antibody |
| Product Description: | Rabbit Polyclonal anti-DRP1 |
| Clonality: | Polyclonal |
| ListPrice: | 285 |
| Concentration: | 0.76 mg/ml |
| Immunogen: | A synthetic peptide made to an N-terminal region within residues 1-100 of the human protein. [Swiss-Prot# O00429] |
| Cross Reactivity: | This antibody reacts with the human and mouse protein. It has not been tested against any other species. |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for Western blot analysis where a band is seen at ~81 kDa. |
| Localization: | Cytoplasm; cytosol. Intracytoplasmic membrane; peripheral mambrane protein. Mainly cytosolic. Also membrane-associated. Localizes to mitochondia at spots of division events. Associated with peroxisomal membranes, it is recruited in part by PEX11B. May also be associated with endoplasmic reticulum tubules and cytoplasmic vesicles and found to be perinuclear. |
| Background: | A human dynamin-related protein, DRP1 contributes to mitochondrial division in mammalian cells. It plays this important role in mitochondrial fission at steady state and during apoptosis. DRP1 is required for proper cellular distribution of mitochondria, and in mutant neurons, mitochondria are largely absent from synapses, thus providing a genetic tool to assess the role of mitochondria at synapses. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Host Name: | Rabbit |
| Buffer: | Tris-glycine, 150mM NaCl |
| Application Summary: | immunohistochemistry , Western Blot |
| Species Summary: | Hu, Mu, , |
| Alternate Names: | anti-Dynamin related protein 1 antibody; anti-DNM1L (Dynamin-1-like protein) antibody; anti-EC 3.6.5.5 antibody; anti-Dynamin-like protein antibody; anti-Dnm1p/Vps1p-like protein antibody; anti-DVLP antibody; anti-Dynamin family member proline-rich carboxyl-terminal domain less antibody; anti-Dymple antibody; anti-Dynamin-related protein 1 antibody; anti-Dynamin-like protein 4 antibody; anti-Dynamin-like protein IV antibody; anti-HdynIV antibody |
| Package Size: | 0.1 ml |
| Preservative: | 0.05% sodium azide |
| Homology: | 100% Human, Monkey, and Hamster |
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more information: | company product webpage |