| request information: |
|
| Catalog Code: | NB110-5029 |
| Product Name: | Caveolin 3 Antibody |
| Product Description: | Rabbit Polyclonal anti-Caveolin 3 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Concentration: | 1 mg/ml |
| Immunogen: | Synthetic peptide: M(1)MTEEHTDLEARIIKDIH(18) C. Immunizing peptide corresponds to amino acid residues 1-18 of human caveolin-3. This sequence is completely conserved in mouse caveolin-3. |
| Specificity: | Detects caveolin-3 from rat tissues. This antibody does not detect caveolin-1 or -2. |
| Cross Reactivity: | Cross-reacts with Human, Rat and Mouse. |
| Packaging: | 0.1 mg Immunogen affinity purified Rabbit antisera. |
| Uses: | Western Blot: use at 1 ug/ml. By Western blot, this antibody detects an ~21 kDa protein representing caveolin-3 from rat heart homogenate. |
| Background: | This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | PBS, 1 mg/ml BSA |
| Application Summary: | immunohistochemistry , immunoprecipitation , Western Blot 1 ug/ml, Immunohistochemistry-Paraffin 1:500 |
| Species Summary: | Hu, Mu, Rt, |
| Alternate Names: | anti-CAV 3 antibody, anti-CAV3 antibody, anti-Caveolin3 antibody, anti-LGMD1C antibody, anti-M caveolin antibody, anti-MGC126100 antibody, anti-MGC126101 antibody, anti-MGC126129 antibody, anti-VIP 21 antibody, anti-VIP21 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.05% sodium azide |
| General References: | Tang Z et al. Molecular cloning of caveolin-3, a novel member of the caveolin gene family expressed predominantly in muscle. J Biol Chem 271:2255-61 (1996). <PUBMED:8567687> |
order or
more information: | company product webpage |