| CatalogCode: | NB110-40901 |
| ProductName: | TCP1 beta Antibody |
| Product Description: | Mouse Monoclonal anti-TCP1 beta (F39 P7 F11) |
| Clone: | F39 P7 F11 |
| Clonality: | Monoclonal |
| Immunogen: | ovalbumin-conjugated sythetic peptide RKRVPDHHPC (C-terminal sequence common to human, frogm mouse, rat). |
| Specificity: | This antibody is specific to the TCP-1 beta protein. |
| CrossReactivity: | Human, Mouse, Rat, and Xenopus. Other species not yet tested. |
| Packaging: | 5 ml Tissue culture supernatant Mouse ascites. |
| Uses: | This antibody is useful for Immunohistochemistry FP, and Western Blot. (antigen retrieval: microwave 20 min at 800W in 10mM citrate buffer, pH6.0) |
| Control: | colorectal, Calu6 adn HT29 cell lysate |
| Background: | TCP1 beta is a subunit of a cytosolic hetero-oligomer chaperone that is known to be involved in the folding of actin and tubulin. This protein is a member of the chaperonin family, which includes Escherichia coli GroEL, the mitochondrial heat-shock protein Hsp60, the plastid Rubisco-subunit-binding protein and the archaebacterial protein TF55. These chaperonins assist the folding of proteins upon ATP hydrolysis. Nine different subunits of TCP-1 containing chaperonin complexes from mammalian testis and seven different subunits of mouse F9 cells have been identified. It has been suggested that each CCT subunit has a specific, independent function, as they are highly diverged from each other but conserved from mammals to yeast. The expansion in the number of types of CCT subunit, compared with other chaperonins, has allowed CCT to carry out more complex functions that are required for the folding and assembly of highly evolved eukaryotic proteins. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Tissue culture supernatant |
| Isotype: | IgG2a kappa |
| Host_Name: | Mouse |
| ListPrice: | 295 |
| AppSummary: | IHC-Fr, IHC-P, WB |
| SpeciesSummary: | Hu, Mu, Rt, Xp |
| ALTnames: | anti-T-comples protein 1 anitbody antibody, anti-beta subunit antibody, anti-chaperonin containing TCP1 antibody, anti-subunit 2 beat antibody, anti-CCT-beta antibody, anti-CCTB antibody |
| PackageSize: | 5 ml |
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