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| Catalog Code: | NB110-40877 |
| Product Name: | ADFP Antibody |
| Product Description: | Rabbit Polyclonal anti-ADFP |
| Clonality: | Polyclonal |
| ListPrice: | 285 |
| Concentration: | 0.84 mg/ml |
| Immunogen: | A synthetic peptide made to a C-terminal region within residues 350-425 of the mouse protein. [Swiss-Prot# P43883] |
| Cross Reactivity: | This antibody is reactive with mouse and human proteins. Other species have not been tested. |
| Packaging: | 0.1 ml peptide affinity purified Rabbit antisera. |
| Uses: | This antibody can be used for Western blot analysis where a band at ~46 kDa is seen. |
| Localization: | Membrane |
| Background: | Milk lipid globules from humans, cows and rats contain a protein identified as adipocyte differentiation-related protein (ADFP). It is associated with the globule surface membrane material. This protein, previously believed to be specific to adipocytes, is a major constituent of the globule surface and is present in a detergent-insoluble complex that contains butyrophilin and xanthine oxidase. ADFP (Adipophilin) is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells. In tissues, however, expression of adipophilin is restricted to specific cell types, such as lactating mammary epithelial cells, adrenal cortex cells, Sertoli and Leydig cells of the male reproductive system, and steatosis or fatty change hepatocytes in alcoholic liver cirrhosis. ADFP may be a possible new marker for the identification of specialized differentiated cells containing lipid droplets and for diseases associated with fat-accumulating cells. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | peptide affinity purified |
| Host Name: | Rabbit |
| Buffer: | PBS + 30% glycerol |
| Application Summary: | Western Blot 2 ug/ml |
| Species Summary: | Hu, Mu, |
| Alternate Names: | anti-Adipophilin antibody, anti-adipose differentiation-related protein antibody, anti-ADRP antibody |
| Package Size: | 0.1 ml |
| Preservative: | No preservative |
| Homology: | 100% with mouse and 88% with rat. |
| General References: | 1. Deanna DiDonato and Dawn L. Brasaemle. J. Histochemistry & Cytochemistry. 51(6): 773-780 (2003) |
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more information: | company product webpage |