| request information: |
|
| Catalog Code: | NB110-40713 |
| Product Name: | PRMT6 Antibody |
| Product Description: | Rabbit Polyclonal anti-PRMT6 |
| Clonality: | Polyclonal |
| ListPrice: | 325 |
| Gene ID: | 55170 |
| Concentration: | 1 mg/ml |
| Immunogen: | The epitope recognized by this antibody maps to a region between residue 325 and the C-terminus (residue 375) of human Protein Arginine Methyltransferase 6 using the numbering given in entry AAK85733.1 (GeneID 55170). |
| Specificity: | This antibody is specific to the human PRMT6 protein. |
| Cross Reactivity: | Human. |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for Immunoprecipitation and Western Blot. Optimal working dilutions should be determined experimentally by the investigator. |
| Background: | PRMT6 severely impairs the function of HIV-1 Rev. PRMT6 is a protein arginine N-methyltransferase, and catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation is a prevalent post-translational modification in eukaryotic cells that has been implicated in signal transduction, the metabolism of nascent pre-RNA, and the transcriptional activation processes. In addition, PRMT6 displays automethylation activity; it is the first PRMT to do so. PRMT6 has been shown to act as a restriction factor for HIV replication. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Host Name: | Rabbit |
| Buffer: | Tris-citrate/phosphate buffer, pH 7 to 8 |
| Application Summary: | immunoprecipitation Not recommended. Use NB 110-40712., Western Blot 1:2,000- 10,000 |
| Species Summary: | Hu |
| Alternate Names: | anti-PRMT6 antibody, anti-PRMT-6 antibody, anti-Protein Arginine Methyltransferase 6 antibody, anti-HRMT1L6 antibody, anti-HMT1 hnRNP Methyltransferase-like 6 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.09% Sodium Azide |
order or
more information: | company product webpage |