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| Catalog Code: | NB110-40680 |
| Product Name: | KIF2A Antibody |
| Product Description: | Rabbit Polyclonal anti-KIF2A |
| Clonality: | Polyclonal |
| ListPrice: | 325 |
| Gene ID: | 3796 |
| Concentration: | 0.2 mg/ml |
| Immunogen: | The epitope recognized by this antibody maps to a region between residue 630 and 679 of human Kinesin Heavy Chain Member 2A using the numbering given in entry NP_004511.1 (GeneID 3796). |
| Specificity: | This antibody is specific to the human KIF2A protein. |
| Cross Reactivity: | Human. |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for Western Blot and Immunoprecipitation. Optimal dilution to be determined by the researcher. |
| Background: | The kinesin-related proteins are involved in functions related to movements of organelles, microtubules, or chromosomes along microtubules. These functions include axonal transport, microtubule sliding during nuclear fusion or division, and chromosome disjunction during meiosis and early mitosis. The kinesins are tetramers composed of 2 heavy and 2 light chains. The N-terminal heavy chain sequences show similarity in all the kinesin-related proteins. The N-terminal part forms the motor domain, with the microtubule-binding region allowing the protein to slide along the microtubule. It also possesses an ATP-binding site allowing an ATPase activity that provides the energy required for the movement. Kinesin-like motor proteins are found in several vertebrate cell types but are most strongly expressed in neuronal cells. In dividing cells it is required for bipolar spindle formation and chromosome segregation. In neuronal cells it is involved in neurite outgrowth. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Host Name: | Rabbit |
| Buffer: | Tris-buffered Saline containing 0.1% BSA |
| Application Summary: | immunoprecipitation 2-5 mcg/mg lysate, Western Blot 1:2,000- 10,000 |
| Species Summary: | Hu |
| Alternate Names: | anti-KIF2 antibody, anti-KIF-2 antibody, anti-Kinesin Heavy Chain Member 2A antibody |
| Package Size: | 0.02 mg |
| Preservative: | 0.09% Sodium Azide |
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more information: | company product webpage |