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| Catalog Code: | NB110-40639 |
| Product Name: | HdmX Antibody |
| Product Description: | Rabbit Polyclonal anti-HdmX |
| Clonality: | Polyclonal |
| ListPrice: | 350 |
| Gene ID: | 4194 |
| Immunogen: | The epitope recognized by this antibody maps to a region between residue 125 and 175 of human ortholog of mouse double minute 4 using the numbering given in Swiss-Prot entry O15151 (GeneID 4194). |
| Specificity: | This antibody is specific to the human HdmX/MDM4 IHC protien. |
| Cross Reactivity: | Human. |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for immunohistochemistry Formalin-Fixed Paraffin-Embedded Tissue. |
| Background: | The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2 |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Host Name: | Rabbit |
| Buffer: | Tris-buffered Saline containing 0.1% BSA |
| Application Summary: | immunohistochemistry 1:100-1:500, |
| Species Summary: | Hu |
| Alternate Names: | anti-HdmX antibody, anti-MdmX antibody, anti-MDM4 antibody, anti-homolog of mouse double minute 4 protein antibody |
| Package Size: | 0.1 ml |
| Preservative: | 0.09% Sodium Azide |
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more information: | company product webpage |