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| Catalog Code: | NB110-40464 |
| Product Name: | Phosphodiesterase 2A Antibody |
| Product Description: | Rabbit Polyclonal anti-Phosphodiesterase 2A |
| Clonality: | Polyclonal |
| ListPrice: | 325 |
| Concentration: | 1.0 mg/ml |
| Immunogen: | Synthetic peptide - KLH conjugated (exact sequence is proprietary information). |
| Epitope: | N-terminal region of human |
| Specificity: | This antibody is specific to the human PDE2A protein. |
| Cross Reactivity: | Human. Other species not yet tested. |
| Packaging: | 0.05 mg peptide affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for immunohistochemistry. Optimal dilution to be determined by the researcher. |
| Localization: | Cell Membrane |
| Background: | Phosphodiesterase 2A is a cGMP stimulated, cAMP/cGMP dual-specific phosphodiesterase whose hydrolytic activity is stimulated by the presence of cGMP binding to the GAF domain. PDE2A has been implicated in penile erectile dysfunction and in the regulation of fluid and inflammatory cell transit across the endothelial cell barrier (i.e., venous and capillary). PDE2A activity is inhibited by erythro-9-(2-hydroxyl-3-nonyl)adenine (EHNA). At least three isoforms have been reported (PDE2A1, PDE2A2, and PDE2A3). |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | peptide affinity purified |
| Host Name: | Rabbit |
| Buffer: | Phosphate buffered saline, PH 7.7 |
| Application Summary: | immunohistochemistry 20 ug/ml |
| Species Summary: | Hu, |
| Alternate Names: | anti-PDE2A antibody; Anti-cGMP dependent 3'5' cyclic phosphodiesterase antibody; Anti-CGS PDE antibody; Anti-cGSPDE antibody; Anti-Cyclic GMP stimulated phosphodiesterase antibody; Anti-Human cGMP stimulated 3'5' cyclic nucleotide phosphodiesterase antibody; Anti-PDE 2A antibody; Anti-PDE 2A1 antibody; Anti-PDE 2A4 antibody; Anti-PDE2A1 antibody; Anti-PDE2A4 antibody; Anti-Phosphodiesterase 2A cGMP stimulated antibody |
| Package Size: | 0.05 mg |
| Preservative: | 0.01% sodium azide |
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more information: | company product webpage |