| CatalogCode: | NB110-40414 |
| ProductName: | Nanog Antibody |
| Product Description: | Rabbit Polyclonal anti-Nanog |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide comprising residues 281-296 [TRYFSTPQTMDLFLNY] of the human Nanog protein. Reactivity in other species unknown. |
| Specificity: | This antibody is specific to the Nanog protein. |
| CrossReactivity: | Human. Other species not yet tested. |
| Packaging: | 0.1 mg Immunogen affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for Western Blot. |
| Background: | The transcriptional factor Nanog functions in maintaining pluripotency in cooperation with other key genes such as Oct4. Oct4 and Sox2 bind to the Nanog promoter in mouse and human embryonic stem cell. Nanog levels allow stem cells to balance the creation of lineage-committed and undifferentiated cells. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | PBS |
| ListPrice: | 285 |
| AppSummary: | WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Nanog Homeobox antibody, anti-Homeobox Transcription Factor Nanog antibody, anti-FLJ12581 antibody |
| PackageSize: | 0.1 mg |
| GeneralRef: | 1. Clark, A.T., Rodriguez, R.T., Bodnar, M.S., Abeyta, M.J., Cedars, M.I., Turek, P.J., Firpo, M.T. and Reijo Pera, R.A. Human STELLAR, NANOG, and GDF3 genes are expressed in pluripotent cells and map to chromosome 12p13, a hotspot for teratocarcinoma. (2004) Stem Cells 22:169-179 2. Mitsui, K., Tokuzawa,Y., Itoh, H., Segawa, K., Murakami, M., Takahashi, K., Maruyama, M., Maeda, M. and Yamanaka, S. The homeoprotein Nanog is required for maintenance of plurioteincy in mouse epiblast and ES cells. (2003) Cell 113:631-642 |
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